Session Index

Biophotonics

Biophotonics II
Friday, Dec. 4, 2015  16:10-17:40
Chair: Shi-Wei Chu
Room: Delta 108(1F)
Notes:
16:10 - 16:40 Paper No.  2015-FRI-S0602-I001
Invited Speaker:
Yoshiaki Yasuno
Simultaneous 3-D imaging of birefringence and flow in in vivo posterior eye


This presentation describes an extension of optical coherence tomography (OCT) and its clinical application for eye imaging. This extension is Jones matrix OCT which is capable of measuring three-dimensional tomography of Jones matrix of tissue. The following tomographies are then derived from the Jones matrix tomography; standard OCT, flow contrast image (OCT-angiography), birefringence tomography, and polarization uniformity tomography. The birefringence tomography selectively visualizes fibrous tissue, while the polarization uniformity tomography is sensitive to melamine concentration. A custom-built clinical prototype of ophthalmic Jones matrix OCT is applied to the investigation of pathologies in the posterior eye, and its clinical utility is discussed based on the clinical findings.

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16:40 - 16:55 Paper No.  2015-FRI-S0602-O001
Yeh Lin A Novel Implementation of Directly-modulated LED into Fluorescence Lifetime Imaging Microscopy


We demonstrated the integration of directly-modulated light emitting diodes (LEDs) into nanosecond-resolved fluorescence lifetime imaging microscopy (FLIM). With costumed LED driving circuit and careful choice of multi-die package, we overcame the limitations of LED to produce light with both high power and high frequency response, even for LED dice in the “green gap” region.

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16:55 - 17:10 Paper No.  2015-FRI-S0602-O002
Chen-Han Lin The Study of Fluorescence Imaging Using Nonlinear Structured-Illumination Enhanced Temporal Focusing Multiphoton Microscopy


The light diffraction of temporal focusing multiphoton excitation microscopy (TFMPEM) and the excitation patterning of nonlinear structured-illumination microscopy (NSIM) can be simultaneously implemented via a single high-resolution digital micromirror device. The lateral and axial spatial resolutions of the TFMPEM are improved through the second-order NSIM.

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17:10 - 17:25 Paper No.  2015-FRI-S0602-O003
Yung-Jhe Yan Research of Visual Fatigue with Accommodative Microfluctuations and Intraocular Pressure on Stereoscopic Displays


Visual fatigue may be caused by access to stereoscopic displays. The high frequency component (HFC) of accommodative microfluctuations and intraocular pressure (IOP) for visual fatigue are investigated by this study. The results of the experiment in the study show the variance of the HFC and IOP for stereoscopic displays.

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17:25 - 17:40 Paper No.  2015-FRI-S0602-O004
Shih-Min Chang Time-resolved diffuse optical tomography system development


We developed a near-infrared time-resolved diffuse optical tomography (NIR-TRDOT) system. And using NIR-TRDOT experiments in-vivo oxygenation dynamic monitoring. Our result shows the differences in change of optical properties with venous and arterial occlusion. We use change of optical properties with occlusion to know microcirculation in clinical diagnosis.

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