Session Index

Biophotonics

Poster Session II
Saturday, Dec. 5, 2015  17:10-18:00
Chair:
Room:
Notes:
Paper No.  2015-SAT-P0602-P001
Sin-Yi Huang In situ monitoring of femtosecond laser induced cavitation with lock-in signal amplification


Femtosecond laser can achieve multiphoton plasma-induced ablation in bio-tissues and cells. In this study, we add a He-Ne laser system to probe ablation processing and the very weak cavitation signal is enhanced by using a lock-in amplifier. By analyzing the probe signals, we can further know some information such as material ablation threshold, and so on.

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Paper No.  2015-SAT-P0602-P002
Yung-Tsan Chen Silicon Photonic Crystal Biosensor


In this study the 2D PhC (Photonic Crystal) biosensor with cost-effective measurement system was developed. The band diagram analysis was applied to accomplish this approach under the low resolution detector. The results showed that the system had potential to detect the specific biding interaction between the antigens and the antibodies.

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Paper No.  2015-SAT-P0602-P003
Cheng-Chih Hsu Study of the Hydrogen peroxide Concentration Measurement by Analysis of the Absorption Spectrum of the Peroxidase method-- Investigate measurement sensitivity variations at different monitored wavelength peak.


The hydrogen peroxide will be converted and interacted with 4-aminophenazone and phenol via peroxidase procedure and will be absorbed the light with the wavelength of 510 nm. In this study, we demonstrated the concentration of the hydrogen peroxide by analyzing the absorption spectrum with spectrometer. The results shown the absorption behavior is inverse proportional to the concentration of the hydrogen peroxide.

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Paper No.  2015-SAT-P0602-P004
Hung-Cheng Lin Hydro-gel light-guiding conjunction for multi-ions detection


We present a novel miniaturized real-time sensor made by two optical fibers embedded in a sensing hydro-gel conjunction. With a multi-wavelength excitation light, mixed solution contains Zn2+ and Fe3+ ions can be detected simultaneously. The concept develops an image for the real-time monitoring of zinc and iron ions in vivo.

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Paper No.  2015-SAT-P0602-P005
Ying-Shuo Chiu Gate-recessed AlGaN/GaN-based Urea Biosensors with ZnO Nanorod Sensing Membrane


To develop the high sensitive urea biosensors, the AlGaN/GaN heterostructure together with ZnO nanorod array were utilized in this work. Furthermore, the photoelectrochemical method was applied to enhance sensing performances. The urea sensitivity of the gate-recessed AlGaN/GaN ISFET urea biosensors with ZnO nanorod array were improved to 20.03 mA/pCurea.

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Paper No.  2015-SAT-P0602-P006
Shyh-Yuan Lee 3D Reconstruction of Teeth and Cracked Teeth using Optical Coherence Tomography


A high speed swept-source optical coherence tomography system was assembled to detect a cracked teeth, and showed the 3D tomography of any section. The 3D images were used to rebuild the appearance of the tooth and the location of crack line.

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Paper No.  2015-SAT-P0602-P007
Chun-Nien Liu Study of Broadband Ce-doped Fibers Using Drawing-tower for OCT Source


The fabrication and characteristics of Ce-doped fibers (CeDFs) using drawing tower are reported. The CeDFs exhibited a 200-nm near-Gaussian broadband emission with 1.8-μm axial resolution and a power density of 79.1 nW/nm. This CeDFs may be functioned as a high-resolution light source for use in optical coherence tomography applications.

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Paper No.  2015-SAT-P0602-P008
Shu Chia Huan Simultaneous three-color two photon fluorescence microscopy by a fiber-optic light source


A novel fiber-based three color femtosecond source and its application on simultaneous imaging of three kinds of fluorescent proteins were demonstrated. The three-band light source was composed of an energetic 1030 nm pulsed source as a fiber-optic wavelength convertor. Finally, the simultaneous imaging on Mouse skin hair follicle cells is performed

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Paper No.  2015-SAT-P0602-P009
Chang Yu Cheng Real time monitoring of H2O2 redox in zebrafish liver in vivo with a sensitive single fiber probe


H2O2 is a ubiquitous reactive oxygen metabolite which is important in cell function regulation. We used a sensitive fiber-optic probe to noninvasively monitor H2O2 redox in transgenic zebrafish which has reversible H2O2-indicating fluorescent protein specifically expressed in the liver in vivo in real time.

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Paper No.  2015-SAT-P0602-P010
Yu-Kuang Chiu In vivo rat cornea characterization using a high resolution OCT


A full-field optical coherence tomography for ophthalmology is developed using a broadband and cw emission from a glass-clad Ti:sapphire crystal fiber. As a demonstration, the cornea of a rat was characterized. The blood flow in cornea also can clearly be seen.

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Paper No.  2015-SAT-P0602-P012
Lin Yu Cheng A Reflection-Type Fiber-Optic Sensor Based on Surface Plasmon Resonance


A reflection-type (R-type) fiber-optic sensor probe based on surface plasmon resonance (SPR) technology is demonstrated. The maximum SPR efficiency is about 45.8% at resonant wavelength 671 nm and 46.2% at 0.696 nm for DI water and alcohol, respectively. The R-type sensor shows better performance in both DI water and alcohol detection than the conventional transmission-type (T-type) sensor.

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Paper No.  2015-SAT-P0602-P013
Hsin-Feng Hsu Detection of Antibody and Antigen Binding Reaction by ARROW-B SPR Sensors


In this study, we detected the binding between antibody and antigen by using antiresonant reflecting optical waveguide B (ARROW-B) surface plasmon resonance (SPR) biosensors. This sensor was designed for the aqueous environment. The experimental results show that the binding of antibody and antigen can be detected by our sensor.

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Paper No.  2015-SAT-P0602-P014
Chi-Wei Meng The Metallic nano thin films in-situ and real-time deposition monitoring based on fiber surface plasmon resonance


We propose a new optical fiber sensor based on surface plasmon resonance that was designed to measure the nano-film thickness of nickel metal for the purpose of in-situ and real-time deposition monitoring. Spectrum responses of the SPR absorption and the normalized transmitted light power at 830-nm wavelength have been demonstrated.

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Paper No.  2015-SAT-P0602-P015
Peng-Wei Lin In vivo breast cancer diagnosis using time-resolved diffuse optical tomography


We have developed a near-infrared time-resolved diffuse optical tomography (NIR-TRDOT) system for in vivo imaging of human breast tissue built by acquired tissue absorption properties. By building breast tissue imaging, we determine the accurate position of breast tumor and thus provide a noninvasive method to detect breast cancer. Overall, this system offers a safe, stable, and rapid way for clinical diagnosis of breast cancer.

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Paper No.  2015-SAT-P0602-P016
Tan Lin Liao System Optimization and Image Processing for Swept-Source Optical Coherence Tomography


we discuss the experimental problems in constructing an SS-OCT system, including image processing and analysis, noise control, and the relationship between signal and data acquisition. We made sure the signals of all the hardware were synchronized timing. And the data analysis process in our programing comprises spectral shaping with Hamming window correction, DC noise deduction, fast Fourier transforms (FFT) and correlation mapping.

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Paper No.  2015-SAT-P0602-P017
YU-YIN LU Study on the Optical-fiber based on Glucose Sensor by using Heterodyne Interferometry


This study demonstrated a novel fiber-type glucose sensor which immobilized the glucose oxidase (GOx) on the no-core fiber (NCF). The glucose will convert to gluconic acid and affect the phase difference between p- and s- polarizations coming from the total internal reflection (TIR) at the interface between NCF and testing sample. The phase variation can be measured precisely by heterodyne interferometer. According to the results, the resolution and sensitivity of the proposed sensor will affect by the length of the NCF. The proposed sensor with 3 cm in length of NCF exhibited high sensitivity and resolution which can be approximately 0.01142 (deg/mg ) and 0.032 (mg/dl), respectively. Besides, the volume of the test sample is less than 1 ml and response time is shorter than 2 sec.

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Paper No.  2015-SAT-P0602-P018
Kai-Shih Chiu Muscle Oxygenation Dynamics in NMES with Near-infrared Spectroscopy Measurement


Neuromuscular electrical stimulation (NMES) are often used to prevent muscle atrophy generally, while the strength and work are confirmed by doctor's experience. In our study, we use near-infrared spectroscopy (NIRS) to measure tissue oxygenation changes within electrical stimulation. To quantify the influence of NMES is helpful on doctors’ diagnosis and has an opportunity to reduce the pain from NMES.

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Paper No.  2015-SAT-P0602-P019
Pavel Rogov Mechanism of femtosecond laser radiation influence on skin


In this paper we presented a mathematical model that describes the linear and nonlinear processes arising from action of femtosecond laser radiation on the skin. We have completed the solution of the equations describing the dynamics of the electron and phonon subsystems. Methods and numerical simulation have shown that threshold damage to the skin under femtosecond pulses radiation increases with decreasing pulse duration. The results of this work can be used to create a laser safety standard for femtosecond laser systems.

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